Welcome to St. Louis, Missouri

St. Louis, often referred to as the "Gateway to the West," is a city rich in history, culture, and innovation. Known for its iconic Gateway Arch, the tallest monument in the United States, St. Louis offers a diverse array of attractions that cater to all interests. From its vibrant arts scene and historic neighborhoods to its renowned culinary offerings and sports culture, St. Louis is a city that promises an unforgettable experience.

Founded in 1764, St. Louis played a pivotal role in the westward expansion of the United States. Today, it stands as a testament to its historical significance while embracing modernity with a thriving tech industry and a burgeoning arts community. Visitors can explore the city's many museums, enjoy its lush parks, and indulge in its famous barbecue and craft beer scene.

Before embarking on your journey, consider booking your flights through Trip.com for the best deals. Once you arrive, you'll find that St. Louis is a city best explored on foot, by bike, or via its efficient public transportation system.

With this 12-day itinerary, you'll have the opportunity to delve deep into the heart of St. Louis, uncovering its hidden gems and experiencing its vibrant culture. Whether you're a history buff, a foodie, or an adventure seeker, St. Louis has something for everyone.

Day 1: Arrival in St. Louis

Arrive in St. Louis in the afternoon and settle into your accommodation. For the best places to stay, consider booking through VRBO or Hotels.com. Spend your first evening exploring the vibrant Delmar Loop, a bustling area known for its eclectic mix of shops, restaurants, and live music venues. Enjoy dinner at Blueberry Hill, a St. Louis institution famous for its burgers and live music.

Day 2: Gateway Arch and Riverfront

Start your day with a visit to the iconic Gateway Arch. Take the tram to the top for breathtaking views of the city and the Mississippi River. Afterward, enjoy a leisurely stroll along the riverfront and consider a river cruise for a unique perspective of the city.

In the afternoon, explore the nearby Laclede's Landing, a historic district with cobblestone streets and charming architecture. For dinner, head to Pappy's Smokehouse for some of the best barbecue in town.

Day 3: Forest Park and Museums

Spend the day exploring Forest Park, one of the largest urban parks in the United States. Visit the St. Louis Art Museum, the Missouri History Museum, and the St. Louis Zoo, all located within the park and offering free admission. Enjoy a picnic lunch in the park's beautiful surroundings.

In the evening, dine at The Boathouse, a lakeside restaurant offering stunning views and delicious American cuisine. After dinner, catch a performance at The Muny, the nation's oldest and largest outdoor musical theater.

Day 4: Soulard and Anheuser-Busch Brewery

Begin your day with a visit to the historic Soulard neighborhood, known for its charming brick architecture and vibrant farmers market. Explore the market and sample local produce and treats.

In the afternoon, take a tour of the Anheuser-Busch Brewery, where you can learn about the brewing process and enjoy a complimentary tasting. For dinner, head to Bogart's Smokehouse for more mouthwatering barbecue.

Day 5: The Hill and Botanical Garden

Spend the morning exploring The Hill, St. Louis's historic Italian neighborhood. Enjoy a delicious breakfast at Missouri Baking Company and wander through the charming streets lined with Italian restaurants and shops.

In the afternoon, visit the Missouri Botanical Garden, one of the oldest botanical gardens in the United States. Stroll through its beautiful gardens and conservatories, and don't miss the stunning Climatron.

For dinner, indulge in authentic Italian cuisine at Charlie Gitto's on The Hill.

Day 6: Science Center and Planetarium

Start your day at the St. Louis Science Center, where you can explore interactive exhibits and learn about science and technology. Don't miss the planetarium for a fascinating journey through the stars.

In the afternoon, head to the Central West End, a vibrant neighborhood known for its historic architecture and trendy shops. Enjoy lunch at a local café and spend the afternoon exploring the area.

For dinner, try Brasserie by Niche, a French-inspired restaurant offering a cozy atmosphere and delicious cuisine.

Day 7: Day Trip to Cahokia Mounds

Take a day trip to Cahokia Mounds, a UNESCO World Heritage Site located just across the river in Illinois. Explore the ancient mounds and learn about the fascinating history of the Mississippian culture.

Return to St. Louis in the evening and enjoy dinner at Sidney Street Café, known for its innovative American cuisine.

Day 8: St. Louis Blues and Nightlife

Spend the morning exploring the vibrant arts scene in the Grand Center Arts District. Visit the Contemporary Art Museum and the Pulitzer Arts Foundation for a dose of modern art.

In the afternoon, catch a St. Louis Blues hockey game at the Enterprise Center for an exciting sports experience. If you're visiting during the off-season, consider a tour of the stadium instead.

After the game, explore the nightlife in the Washington Avenue district, known for its lively bars and clubs. Enjoy a late-night snack at Pi Pizzeria, famous for its deep-dish pizza.

Day 9: Historic St. Charles

Take a day trip to the charming town of St. Charles, located just a short drive from St. Louis. Stroll along Main Street, lined with historic buildings, shops, and restaurants.

Visit the Lewis & Clark Boathouse and Museum to learn about the famous explorers' journey. Enjoy lunch at a local café and spend the afternoon exploring the town's unique boutiques and galleries.

Return to St. Louis in the evening and dine at Tony's, a renowned fine dining restaurant offering exquisite Italian cuisine.

Day 10: Shopping and Entertainment

Spend the day shopping at the St. Louis Galleria, a premier shopping destination with a wide range of stores and dining options. Enjoy lunch at one of the mall's many restaurants.

In the afternoon, visit the City Museum, a unique attraction featuring interactive exhibits and whimsical art installations. Climb through tunnels, slide down chutes, and explore the museum's many wonders.

For dinner, head to The Crossing, a contemporary American restaurant known for its seasonal menu and elegant atmosphere.

Day 11: Outdoor Adventures

Spend the day exploring the great outdoors at Castlewood State Park, located just outside the city. Hike the scenic trails, enjoy a picnic by the river, and take in the beautiful natural surroundings.

In the evening, return to St. Louis and enjoy dinner at Farmhaus, a farm-to-table restaurant offering fresh, locally sourced dishes.

Day 12: Departure

On your final day, enjoy a leisurely breakfast at Rooster, a popular brunch spot known for its crepes and breakfast fare. Spend the morning exploring any last-minute attractions or shopping for souvenirs.

As you prepare to depart, consider booking your return flight through Trip.com for a seamless travel experience.

Summary

This 12-day itinerary offers a comprehensive exploration of St. Louis, Missouri, highlighting its rich history, vibrant culture, and diverse attractions. From iconic landmarks like the Gateway Arch to hidden gems in historic neighborhoods, you'll experience the best of what this dynamic city has to offer. Whether you're a history enthusiast, a foodie, or an adventure seeker, St. Louis promises an unforgettable journey.