Panama, a country bridging two continents, is a land of contrasts where modern skyscrapers meet lush rainforests. Known for the iconic Panama Canal, this vibrant nation offers a rich tapestry of history, culture, and natural beauty. From the bustling streets of Panama City to the serene highlands of Boquete, Panama promises an unforgettable journey.

With a budget-friendly approach, this 10-day itinerary is designed to provide a relaxing yet enriching experience. You'll explore the best of Panama's cities, indulge in local coffee and wine, and enjoy leisurely shopping sprees. Whether you're wandering through the historic Casco Viejo or sipping coffee in the highlands, Panama's charm is sure to captivate you.

Practical travel tips: Panama uses the US dollar, making transactions straightforward for American travelers. The local cuisine is a delightful mix of indigenous, African, and Spanish influences, with seafood being a highlight. Remember to pack light, breathable clothing for the tropical climate, and don't forget your sunscreen!

Panama City

Panama City, the vibrant capital, is a bustling metropolis with a rich history and a modern skyline. Known for the Panama Canal, this city is a hub of commerce and culture. Explore the historic Casco Viejo, a UNESCO World Heritage site, with its charming cobblestone streets and colonial architecture. The city's culinary scene is diverse, offering everything from traditional Panamanian dishes to international cuisine.

For accommodations, consider staying at a centrally located hotel or a cozy VRBO apartment. Check out options on Hotels.com or VRBO for the best deals.

Day 1: Arrival in Panama City

Afternoon: Arrive in Panama City and check into your accommodation. Take a leisurely stroll through the historic Casco Viejo, where you can admire the colonial architecture and vibrant street art.

Evening: Enjoy dinner at Donde José, a renowned restaurant offering a tasting menu that showcases Panamanian flavors. Reservations are recommended.

Day 2: Exploring Panama City

Morning: Start your day with a visit to the Panama Canal. Join the Panama Canal Partial Tour to witness the engineering marvel in action.

Afternoon: Head to the Amador Causeway for lunch at Mi Ranchito, a local favorite known for its seafood and stunning views of the city skyline.

Evening: Explore the nightlife in Casco Viejo. Visit La Rana Dorada, a popular brewery offering a variety of craft beers.

Day 3: Coffee and Culture

Morning: Enjoy a leisurely breakfast at Mentiritas Blancas, a charming coffee shop known for its artisanal brews and pastries.

Afternoon: Visit the Biomuseo, designed by Frank Gehry, to learn about Panama's biodiversity and cultural history.

Evening: Dine at Intimo, a farm-to-table restaurant offering innovative dishes made with local ingredients.

Boquete

Nestled in the highlands, Boquete is a haven for nature lovers and coffee enthusiasts. Known for its cool climate and lush landscapes, this charming town offers a peaceful retreat from the hustle and bustle of city life. Boquete is famous for its coffee plantations, where you can sample some of the world's finest brews.

For accommodations, consider a cozy cabin or a boutique hotel. Explore options on Hotels.com or VRBO.

Day 4: Travel to Boquete

Morning: Depart for Boquete. You can take a domestic flight from Panama City to David, followed by a scenic drive to Boquete. Book your flight on Trip.com.

Afternoon: Arrive in Boquete and check into your accommodation. Spend the afternoon exploring the town's charming streets and local shops.

Evening: Enjoy dinner at The Rock, a restaurant known for its international cuisine and cozy atmosphere.

Day 5: Coffee Plantation Tour

Morning: Visit a local coffee plantation for a guided tour. Learn about the coffee-making process and sample freshly brewed coffee.

Afternoon: Have lunch at RetroGusto, a popular spot offering Italian-inspired dishes made with local ingredients.

Evening: Relax with a glass of wine at Boquete Brewing Company, where you can enjoy live music and a laid-back vibe.

Day 6: Nature and Relaxation

Morning: Explore the stunning landscapes of Boquete with a hike to the Lost Waterfalls. The trail offers breathtaking views and the chance to see local wildlife.

Afternoon: Enjoy a leisurely lunch at Big Daddy's Grill, known for its fresh seafood and friendly atmosphere.

Evening: Unwind with a relaxing evening at your accommodation, perhaps enjoying a book or a quiet walk in the gardens.

Bocas del Toro

Bocas del Toro, an archipelago on the Caribbean coast, is a paradise of turquoise waters and white sandy beaches. Known for its vibrant marine life and laid-back atmosphere, Bocas del Toro is perfect for those seeking relaxation and adventure. The islands offer a range of activities, from snorkeling and diving to exploring the local culture.

For accommodations, consider a beachfront villa or a charming guesthouse. Explore options on Hotels.com or VRBO.

Day 7: Travel to Bocas del Toro

Morning: Depart for Bocas del Toro. You can take a domestic flight from David to Bocas del Toro. Book your flight on Trip.com.

Afternoon: Arrive in Bocas del Toro and check into your accommodation. Spend the afternoon relaxing on the beach or exploring the local shops.

Evening: Enjoy dinner at El Ultimo Refugio, a waterfront restaurant known for its fresh seafood and creative cocktails.

Day 8: Island Hopping Adventure

Embark on a day tour to explore the beautiful islands of Bocas del Toro. Visit Isla Bastimentos, known for its pristine beaches and vibrant coral reefs. Enjoy snorkeling, swimming, and soaking up the sun.

Day 9: Relaxation and Exploration

Morning: Start your day with a leisurely breakfast at Om Café, a popular spot offering healthy options and delicious smoothies.

Afternoon: Explore the local culture with a visit to the Bocas del Toro Museum, where you can learn about the history and traditions of the region.

Evening: Enjoy a sunset dinner at Buena Vista, a restaurant offering stunning views and a menu featuring local and international dishes.

Day 10: Departure

Morning: Spend your final morning relaxing on the beach or enjoying a leisurely breakfast at your accommodation.

Afternoon: Depart for Panama City to catch your flight home. Book your return flight on Trip.com.

This 10-day itinerary offers a perfect blend of relaxation and adventure, allowing you to experience the best of Panama's culture, nature, and cuisine. From the bustling streets of Panama City to the serene landscapes of Boquete and the idyllic beaches of Bocas del Toro, this journey promises unforgettable memories.