Few American cities feel as much like a foreign country as New Orleans. Founded by the French in 1718, ruled for decades by the Spanish, and shaped by Caribbean, African, and Creole traditions, the city guards a culture all its own, from the ironwork balconies of the French Quarter to the birthplace of jazz along the Mississippi. Locals still greet strangers with a warm 'where y'at,' and any excuse (a saint's day, a funeral, a Tuesday) can become a parade.

The food alone justifies the trip: gumbo, jambalaya, po'boys dressed with remoulade, chargrilled oysters, and sugar-dusted beignets served around the clock at Cafe du Monde. Beyond the plate, you can drift past alligators in the Honey Island Swamp, wander the crumbling tombs of the above-ground 'Cities of the Dead,' tour the acclaimed National WWII Museum, and end every night chasing brass bands down Frenchmen Street.

Practically, the compact French Quarter and neighboring Marigny are walkable, and the historic St. Charles streetcar (a $1.25 ride) glides out to the oak-shaded Garden District. Summers are hot and humid with frequent afternoon storms, so spring and fall are ideal, while Mardi Gras and Jazz Fest bring crowds and premium prices. Keep your wits after dark, stick to busy streets, and pace the famously strong drinks.